Top 7 Supplements to Curb Stress and Anxiety
Are you feeling stressed and anxious? Are you looking for something to help you de-stress and stay calm? 

Stress is a normal part of life. We all feel it often, whether it’s before a final exam in college, while working on a project for work, during big changes in your life that you need to adjust to, or whatever the situation may be.

A certain amount of stress is good for us. Stress helps our body react to danger and changes, and helps keep us alert when needed. However, when stress becomes constant, overwhelming and too much to handle, you may need a little help, because too much stress is not good for you and can lead to many health problems.

Right now, stress and anxiety are still high for many people. Our world has changed and its only natural to feel stressed and anxious about our future.

The good news is that the right nutrients and supplements can help support your body’s stress response for optimal health, despite adverse or very demanding circumstances. Here are our top 7 supplements to help curb stress and anxiety. 

Top 7 Supplements to Curb Stress and Anxiety


Dr. Steven Hotze, who has experience in treating patients naturally since 1989, took his top three supplements for calming and mood support and combined them into a synergistic formula to help decrease stress and anxiety, and to help calm your mood. It’s called TranquilTranquil contains 100 mg of Hemp Oil Powder, 100 mg of L-Theanine and 500 mg of Inositol, the first 3 in our top 7 list of supplements to curb stress and anxiety. 

NOTE: Tranquil is not for children. Only if the child is of adult weight, over 100 lbs. or more, then they may be able to take Tranquil. It is always best to consult with your provider first.

1. Hemp Oil Powder: Studies have found that Hemp Oil Powder supports healthy neurotransmitter levels. When Hemp Oil Powder activates cannabinoid receptors, it encourages the body to balance its production and secretion of neurotransmitters to support a healthy mood, a positive outlook on life, sharp memory, and cognitive function.

Research reports that cannabidiol use is effective for stress, sleep problems, and anxiety. (1) Cannabidiol is a phytocannabinoid constituent of Cannabis sativa that lacks the psychoactive effects of 9-tetrahydrocannabinol (THC). Cannabidiol has broad therapeutic properties across a range of neuropsychiatric disorders, stemming from diverse central nervous system actions. (2)

Current evidence indicates cannabidiol has considerable potential as a treatment for multiple anxiety disorders. Evidence conclusively demonstrates cannabidiol’s efficacy in reducing anxiety behaviors relevant to multiple disorders, including post-traumatic stress disorder (PTSD), generalized anxiety disorder, panic disorder, obsessive-compulsive disorder, and social anxiety disorder. (2) 

2. L-Theanine is an amino acid found mainly in tea (especially green tea) and is known to promote a calm and a healthy response to stress. Research findings suggest that L-Theanine has the potential to promote mental health in people with stress-related ailments and cognitive impairments. (3)

3. Inositol is a water soluble B-vitamin that helps quiet brain chatter. It can help you to focus. Inositol is very effective at relieving mental stress from a busy mind. Clinical trials indicate that inositol may be effective in the treatment of patients with depression, panic disorder and obsessive compulsive disorder (OCD). It has been shown to reduce anxiety-like behaviors in animals. (4) Research findings also suggest that inositol may be beneficial for depressed patients. (5)

4. Magnesium is essential for health and is a very helpful supplement during stressful times. Magnesium helps you to relax and stay calm. About 300 enzymatic reactions in the body, including reactions affecting heartbeat, sleep, energy, hormone production and stress hormones, rely on proper levels of magnesium for optimal function. When the body has low magnesium levels, it will tense up, which can cause you to feel stressed, and even cause a tension headache or migraine, as well as cricks in the neck or muscle cramps, and even possibly a heart attack.

Magnesium is an essential element involved in reactions regulating the body’s stress response at several levels. A chronic magnesium deficiency appears to be common among the general population and even more so among those suffering from a number of chronic diseases or stress. (6)

Over the past decades, increasing evidence has investigated and supported the link between magnesium deficiency and increased susceptibility to stress disorders, and further suggested that stress itself can lead to magnesium depletion. (6)

5. Rhodiola is an adaptogenic herb shown to reduce stress. It also helps improve brain function during long or stressful days. Rhodiola rosea L. has a long history of use in traditional medicine to stimulate the nervous system, treat stress-induced fatigue and depression, enhance physical performance and work productivity and treat gastrointestinal ailments and impotence. Many research studies demonstrate that Rhodiola is effective in terms of cognitive functions and mental performance, including various symptoms of life-stress, fatigue and burnout. (7)

6.  Phosphatidyl Serine is a fat-soluble brain nutrient that helps improve memory and also reduces stress. It can actually help you get to sleep after a stressful day. Supplementation with phosphatidylserine has been observed to normalize stress induced dysregulations of the hypothalamus-pituitary-adrenal axis (HPAA). (8)

7. 5-HTP (5-Hydroxytryptophan) helps reduce the anxiety that we feel in a stressful situation. Take one capsule 30 minutes before a meal, up to 3 times daily. It will help brighten moods and boost memory. It can even help reduce the carbohydrate cravings that often increase in stressful times. Also, if you take it at bedtime, it can help you fall asleep. Research demonstrates that a significant reduction in anxiety was observed in patients treated with 5-HTP, suggesting that it may be involved in the mediation of anxiety. (9)

Please note that 5-HTP cannot be taken if you are currently taking an antidepressant medication. Please consult with your provider.

Lifestyle Tips 

There are things you can do every day to help prevent and relieve stress and anxiety. Try meditation and yoga. Get up and move – exercise, go for a walk or run. Physical activity can help boost the production of your endorphins, which are your brain's feel-good neurotransmitters.

Be sure to eat healthy – lots of organic vegetables and fruits. Avoid the junk - sugar, processed and fast food. You’ve probably heard the saying “Garbage in, garbage out.” If you eat poorly, you will feel it both physically and mentally. Take good care of your body and feed it the nutrients it needs. Be sure to stay hydrated and drink lots of water throughout the day, as well. 

Make time to relax. Always get a good night’s sleep. You know how unrefreshed you can feel when you don’t get much sleep or good, sound sleep, and that can only add to your stress. Take a hot bath with Epsom salts. Epsom salts are magnesium sulfate and can help relax your whole body.

We Are Here For You

At Physicians Preference Vitamins, we are here for you. If you have questions about supplements to help get your stress levels in check, or for any other health concerns, please call our Certified Holistic Nutritionists and Vitamin Consultants today at 281-646-1659. It will be our privilege to serve you!