Posted by Physicians Preference Vitamins on 6/29/2023 to Vitamins and Supplements
Do your knees or hips hurt when you go for a walk or run? Are you starting to have pain and stiffness in one or more of your joints? Is it difficult going up the stairs in your home? Joint pain, stiffness and swelling can negatively affect your quality of life. We have a natural solution that can help you with all your joint discomfort so you can get relief and move about much easier.
Osteoarthritis is the most common form of arthritis that affects over 32.5 million US adults. It is caused by damage or breakdown of joint cartilage between the bones over time. Some people call it degenerative joint disease or “wear and tear” arthritis. It occurs most frequently in the hands, hips, and knees. (2)
Globally, the prevalence of osteoarthritis, particularly of the large weight-bearing joints such as the knee and hip, is predicted to grow. Presently, osteoarthritis has emerged as one of the major public health concerns and continues to affect about 10% of men and 18% of women over 60 years of age. (2)
Symptoms of Osteoarthritis
- joint pain and stiffness
- decreased range of motion or flexibility
Causes/Risk Factors for Osteoarthritis (2)
- Joint injury or overuse, such as knee bending and repetitive stress on a joint, can damage a joint and increase the risk of osteoarthritis in that joint.
- The risk of developing osteoarthritis increases with age.
- Women are more likely to develop osteoarthritis than men, especially after age 50.
- The extra weight with obesity puts more stress on joints, particularly weight-bearing joints like the hips and knees. This stress increases the risk of osteoarthritis in that joint. Obesity may also have metabolic effects that increase the risk of osteoarthritis.
- People who have family members with osteoarthritis are more likely to develop osteoarthritis. People who have had osteoarthritis are more likely to develop knee osteoarthritis.
- Some Asian populations have lower risk for osteoarthritis.
Rheumatoid arthritis is an autoimmune and inflammatory disease, which means that your immune system attacks healthy cells in your body causing inflammation and painful swelling.(3)
Rheumatoid arthritis mainly attacks the joints – often several different joints at once. It commonly affects joints in the hands, wrists, and knees. The lining of the joint becomes inflamed, causing damage to joint tissue. This tissue damage can cause long-lasting or chronic pain, lack of balance and deformity. It can also affect other tissues throughout the body and cause problems in the lungs, heart, and eyes. (3)
Signs and Symptoms of Rheumatoid Arthritis (3)
- pain or aching in more than one joint
- stiffness in more than one joint
- tenderness and swelling in more than one joint
- bilateral symptoms (such as in both hands or both knees)
- weight loss
- fatigue or tiredness
With rheumatoid arthritis, there are times when symptoms get worse, known as flares, and times when symptoms get better, known as remission. (3)
Risk Factors for Rheumatoid Arthritis (3):
- Rheumatoid arthritis can begin at any age, but the likelihood increases with age. Its onset is highest among adults in their sixties.
- New cases of rheumatoid arthritis are typically two-to-three times higher in women than men.
- People born with specific genes are more likely to develop rheumatoid arthritis. These genes, called HLA (human leukocyte antigen) class II genotypes, can also make your arthritis worse. The risk of rheumatoid arthritis may be highest when people with these genes are exposed to environmental factors like smoking or when a person is obese.
- Multiple studies show that cigarette smoking increases a person’s risk of developing rheumatoid arthritis and can make the disease worse.
- Women who have never given birth may be at greater risk of developing rheumatoid arthritis.
- Some early life exposures may increase risk of developing rheumatoid arthritis in adulthood. For example, one study found that children whose mothers smoked had double the risk of developing rheumatoid arthritis as adults. Children of lower income parents are at increased risk of developing rheumatoid arthritis as adults.
- Obesity. Being obese can increase the risk of developing rheumatoid arthritis. Studies examining the role of obesity also found that the more overweight a person was, the higher his or her risk of developing rheumatoid arthritis became.
Joint Comfort for Joint Pain Relief
Physicians Preference Vitamins’ Joint Comfort is a comprehensive formula that includes Glucosamine, Chondroitin, Methylsulfonylmethane (MSM), Bromelain, and Boswellia. It does not contain any sugar, wheat, yeast, milk, eggs or soy. This specialized formula provides you with optimal joint support. Let us tell you more about how the ingredients help relieve joint pain and stiffness:
Glucosamine and Chondroitin
- Glucosamine and Chondroitin renew cartilage and improve mobility.
- Glucosamine is an amino sugar that stimulates the production of collagen, enabling your body to rebuild, restore and repair damaged cartilage and tendons.
- It also aids your body to produce synovial fluid which lubricates your joints, allowing smoother joint movement and increased flexibility.
- Chondroitin is derived from shark cartilage and provides the primary component of cartilage, thus helping to maintain the health of the cartilage that cushions your joints.
Glucosamine and chondroitin are structural components of cartilage, the tissue that cushions the joints. Both are produced naturally in the body and they are also available as supplements. Researchers have studied the effects of these supplements, individually or in combination, on osteoarthritis, a common type of arthritis that destroys cartilage in the joints, and they help relieve joint pain and slow the rate of joint destruction and cartilage loss. (2,4)
Research results show that oral chondroitin is more effective than placebo in relieving pain and improving physical function. Compared with placebo, glucosamine showed significant effect on the outcome of stiffness. (4)
MSM is a naturally occurring organosulfur compound with broad biological effects. MSM supplementation has been shown to improve inflammation, joint and muscle pain, oxidative stress, and antioxidant capacity. This micronutrient can be used for arthritis and a number of other conditions related to inflammation, physical function, and performance. (5)
- Your body needs healthy connective tissue, such as cartilage, tendons and ligaments, to enable your joints to operate effectively.
- MSM provides a natural form of sulfur which your body can use to make strong connective tissue.
- It is actually one of the most prominent compounds in our bodies, just behind water and sodium.
- It improves joint flexibility, reduce stiffness and swelling in joints, reducing pain and scar tissue.
- Increases blood flow to deliver nutrients to the injured tissues.
Bromelain, which is obtained from both the stem and fruit of the pineapple plant, contains a number of proteolytic enzymes and has been demonstrated to show anti-inflammatory and analgesic properties. Bromelain is a special enzyme that breaks down long chains of proteins into smaller chains and even into individual amino acids, which helps your body digest and absorb the joint-nourishing, cartilage-building sulfates. It can provide a safer alternative or adjunctive treatment for osteoarthritis. Currently, bromelain is used for acute inflammation and sports injuries. (6)
Boswellia serrata is a moderate to large sized branching tree native to India, Africa and the Middle East. Boswellia prevents substances that cause swelling from forming in your joints. Research findings provide clinical evidence to support that Boswellia exerts anti-inflammatory and anti-arthritic activity in reducing joint pain and improving the physical functional ability. (7)
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1. Effectiveness and Safety of Glucosamine and Chondroitin for the Treatment of Osteoarthritis: A Meta-Analysis of Randomized Controlled Trials
4. Effectiveness and Safety of Glucosamine and Chondroitin for the Treatment of Osteoarthritis: A Meta-Analysis of Randomized Controlled Trials